Disable USB Removable Mass Storage Device Drive Access in Windows

1. Run Registry Editor (regedit).
2. Navigate to the following registery key

   HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\UsbStor

3. In the right pane, double click on the Start value name.
4. Change the value data to 4 to disable the removable USB mass storage device drive access.
5. To revert and re-enable the drive access for removable USB mass storage device driver, change back the value data for Start to its original default of 3.